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Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus

BACKGROUND: Foot-and-mouth disease virus (FMDV) exhibits a high degree of antigenic variability. Studies of the antigenic diversity and determination of amino acid changes involved in this diversity are important to the design of broadly protective new vaccines. Although extensive studies have been...

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Bibliografiske detaljer
Main Authors: Xue, Mei, Wang, Haiwei, Li, Wan, Zhou, Guohui, Tu, Yabin, Yu, Li
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489780/
https://ncbi.nlm.nih.gov/pubmed/22963009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-191
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