Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity

The glutamate-aspartate transporter GLAST is a radial glia marker that is highly expressed in GL261 stem-like cells (GSCs). To target GLAST, we treated glioma-bearing mice with three subcutaneous injections of four GLAST peptides emulsified with Montanide ISA-51 in association with granulocyte macro...

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Autores principales: Cantini, Gabriele, Pisati, Federica, Pessina, Sara, Finocchiaro, Gaetano, Pellegatta, Serena
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489744/
https://ncbi.nlm.nih.gov/pubmed/23162756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20637
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