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The multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma
Abcc3, a member of the ATP-binding cassette transporter superfamily, plays a role in multidrug resistance. Here, we found that Abcc3 is highly expressed in blood-derived NK cells but not in CD8(+) T cells. In GL261 glioma-bearing mice treated with the alkylating agent temozolomide (TMZ) for 5 d, an...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910710/ https://ncbi.nlm.nih.gov/pubmed/27467914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1108513 |
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