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An ENU mutagenesis approach to dissect “self”-induced immune responses: Unraveling the genetic footprint of immunosurveillance

The immune system exerts a critical function as it recognizes and eliminates transformed or neoplastic cells, a process also referred to as immunosurveillance. NK cells play a particularly important role in that they are able to recognize tumor cells via “missing-self”—i.e., the absence of major his...

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Hlavní autoři: Cashman, Siobhan, Lampe, Kristin, Sheridan, Rachel, Hoebe, Kasper
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489741/
https://ncbi.nlm.nih.gov/pubmed/23162753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20580
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