L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro

L-carnitine (LC) is generally believed to transport long-chain acyl groups from fatty acids into the mitochondrial matrix for ATP generation via the citric acid cycle. Based on Warburg's theory that most cancer cells mainly depend on glycolysis for ATP generation, we hypothesize that, LC treatm...

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Autori principali: Huang, Hongbiao, Liu, Ningning, Guo, Haiping, Liao, Siyan, Li, Xiaofen, Yang, Changshan, Liu, Shouting, Song, Wenbin, Liu, Chunjiao, Guan, Lixia, Li, Bing, Xu, Li, Zhang, Change, Wang, Xuejun, Dou, Q. Ping, Liu, Jinbao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489732/
https://ncbi.nlm.nih.gov/pubmed/23139833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049062
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