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Treatment with a Nitric Oxide-Donating NSAID Alleviates Functional Muscle Ischemia in the Mouse Model of Duchenne Muscular Dystrophy

In patients with Duchenne muscular dystrophy (DMD) and the standard mdx mouse model of DMD, dystrophin deficiency causes loss of neuronal nitric oxide synthase (nNOSμ) from the sarcolemma, producing functional ischemia when the muscles are exercised. We asked if functional muscle ischemia would be e...

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書誌詳細
主要な著者: Thomas, Gail D., Ye, Jianfeng, De Nardi, Claudio, Monopoli, Angela, Ongini, Ennio, Victor, Ronald G.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489726/
https://ncbi.nlm.nih.gov/pubmed/23139842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049350
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