Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation

BACKGROUND: Exposure to particulate matter (PM) is a significant risk factor for increased cardiopulmonary morbidity and mortality. The mechanism of PM-mediated pathophysiology remains unknown. However, PM is proinflammatory to the endothelium and increases vascular permeability in vitro and in vivo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Ting, Wang, Lichun, Moreno-Vinasco, Liliana, Lang, Gabriel D, Siegler, Jessica H, Mathew, Biji, Usatyuk, Peter V, Samet, Jonathan M, Geyh, Alison S, Breysse, Patrick N, Natarajan, Viswanathan, Garcia, Joe G N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489700/
https://ncbi.nlm.nih.gov/pubmed/22931549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-9-35
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