Particulate Matter Disrupts Human Lung Endothelial Barrier Integrity via ROS- and p38 MAPK–Dependent Pathways

Epidemiologic studies have linked exposure to airborne pollutant particulate matter (PM) with increased cardiopulmonary mortality and morbidity. The mechanisms of PM-mediated lung pathophysiology, however, remain unknown. We tested the hypothesis that PM, via enhanced oxidative stress, disrupts lung...

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Hauptverfasser: Wang, Ting, Chiang, Eddie T., Moreno-Vinasco, Liliana, Lang, Gabriel D., Pendyala, Srikanth, Samet, Jonathan M., Geyh, Alison S., Breysse, Patrick N., Chillrud, Steven N., Natarajan, Viswanathan, Garcia, Joe G. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848737/
https://ncbi.nlm.nih.gov/pubmed/19520919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0402OC
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