Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs

BACKGROUND: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is widely used for quantitative proteomic investigations. The typical output of such studies is a list of identified and quantified peptides. The biological and clinical interest is, however, usually focused on quanti...

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Hlavní autoři: Clough, Timothy, Thaminy, Safia, Ragg, Susanne, Aebersold, Ruedi, Vitek, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489535/
https://ncbi.nlm.nih.gov/pubmed/23176351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S16-S6
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