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Integrated use of LC/MS/MS and LC/Q-TOF/MS targeted metabolomics with automated label-free microscopy for quantification of purine metabolites in cultured mammalian cells

Purine metabolites have been implicated as clinically relevant biomarkers of worsening or improving Parkinson’s disease (PD) progression. However, the identification of purine molecules as biomarkers in PD has largely been determined using non-targeted metabolomics analysis. The primary goal of this...

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Détails bibliographiques
Publié dans:Purinergic Signal
Auteurs principaux: Nybo, S. Eric, Lamberts, Jennifer T.
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439090/
https://ncbi.nlm.nih.gov/pubmed/30604179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-018-9643-2
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