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Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export

The presence of lipopolysaccharide (LPS) on the cell surface of Gram-negative bacteria is critical for viability. A conserved β-barrel membrane protein LptD translocates LPS from the periplasm across the outer membrane (OM). In Escherichia coli, this protein contains two disulfide bonds and forms th...

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Detalhes bibliográficos
Main Authors: Chng, Shu-Sin, Xue, Mingyu, Garner, Ronald A., Kadokura, Hiroshi, Boyd, Dana, Beckwith, Jonathan, Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489181/
https://ncbi.nlm.nih.gov/pubmed/22936569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1227215
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