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Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli

The outer membrane of most Gram-negative bacteria is made up of LPS, and in nearly all bacteria that contain LPS it is essential for the life of the organism. The lipid portion of this molecule, lipid A, also known as endotoxin, is a potent activator of the innate immune response. More than 50 genes...

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Bibliografiske detaljer
Main Authors: Wu, Tao, McCandlish, Andrew C., Gronenberg, Luisa S., Chng, Shu-Sin, Silhavy, Thomas J., Kahne, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544242/
https://ncbi.nlm.nih.gov/pubmed/16861298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604744103
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