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Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli

The outer membrane of most Gram-negative bacteria is made up of LPS, and in nearly all bacteria that contain LPS it is essential for the life of the organism. The lipid portion of this molecule, lipid A, also known as endotoxin, is a potent activator of the innate immune response. More than 50 genes...

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Main Authors: Wu, Tao, McCandlish, Andrew C., Gronenberg, Luisa S., Chng, Shu-Sin, Silhavy, Thomas J., Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544242/
https://ncbi.nlm.nih.gov/pubmed/16861298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604744103
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