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Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration

Airway smooth muscle cell (ASMC) remodeling contributes to the structural changes in the airways that are central to the clinical manifestations of asthma. Ca(2+) signals play an important role in ASMC remodeling through control of ASMC migration and hypertrophy/proliferation. Upregulation of STIM1...

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Detaylı Bibliyografya
Asıl Yazarlar: Spinelli, Amy M., González-Cobos, José C., Zhang, Xuexin, Motiani, Rajender K., Rowan, Sarah, Zhang, Wei, Garrett, Joshua, Vincent, Peter A., Matrougui, Khalid, Singer, Harold A., Trebak, Mohamed
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489062/
https://ncbi.nlm.nih.gov/pubmed/23014880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1160-5
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