Role of the microenvironment in mantle cell lymphoma: IL-6 is an important survival factor for the tumor cells

Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma frequently involved in the lymph nodes, bone marrow, spleen, and gastrointestinal tract. We examined the role of IL-6 in MCL. Human MCL cells expressed the membrane gp130 and soluble gp80, and some of them also secreted IL-6. Ne...

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Detalhes bibliográficos
Main Authors: Zhang, Liang, Yang, Jing, Qian, Jianfei, Li, Haiyan, Romaguera, Jorge E., Kwak, Larry W., Wang, Michael, Yi, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488890/
https://ncbi.nlm.nih.gov/pubmed/22968454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-424630
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