Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction

The mechanical properties of the extracellular matrix have recently been shown to promote myofibroblast differentiation and lung fibrosis. Mechanisms by which matrix stiffness regulates myofibroblast differentiation are not fully understood. The goal of this study was to determine the intrinsic mech...

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Главные авторы: Huang, Xiangwei, Yang, Naiheng, Fiore, Vincent F., Barker, Thomas H., Sun, Yi, Morris, Stephan W., Ding, Qiang, Thannickal, Victor J., Zhou, Yong
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2012
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488695/
https://ncbi.nlm.nih.gov/pubmed/22461426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0050OC
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