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Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction

The mechanical properties of the extracellular matrix have recently been shown to promote myofibroblast differentiation and lung fibrosis. Mechanisms by which matrix stiffness regulates myofibroblast differentiation are not fully understood. The goal of this study was to determine the intrinsic mech...

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Detalhes bibliográficos
Main Authors: Huang, Xiangwei, Yang, Naiheng, Fiore, Vincent F., Barker, Thomas H., Sun, Yi, Morris, Stephan W., Ding, Qiang, Thannickal, Victor J., Zhou, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488695/
https://ncbi.nlm.nih.gov/pubmed/22461426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0050OC
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