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Hypoxic enhancement of exosome release by breast cancer cells

BACKGROUND: Exosomes are nanovesicles secreted by tumour cells which have roles in paracrine signalling during tumour progression, including tumour-stromal interactions, activation of proliferative pathways and bestowing immunosuppression. Hypoxia is an important feature of solid tumours which promo...

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Detalhes bibliográficos
Main Authors: King, Hamish W, Michael, Michael Z, Gleadle, Jonathan M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488584/
https://ncbi.nlm.nih.gov/pubmed/22998595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-421
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