Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

BACKGROUND: We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In this current study, we for the first time examined methyla...

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Detalhes bibliográficos
Main Authors: Waraya, Mina, Yamashita, Keishi, Katoh, Hiroshi, Ooki, Akira, Kawamata, Hiroshi, Nishimiya, Hiroshi, Nakamura, Kazunori, Ema, Akira, Watanabe, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488580/
https://ncbi.nlm.nih.gov/pubmed/22958219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-397
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