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Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis
BACKGROUND: We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In this current study, we for the first time examined methyla...
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Κύριοι συγγραφείς: | , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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BioMed Central
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488580/ https://ncbi.nlm.nih.gov/pubmed/22958219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-397 |
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