Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

<p>Abstract</p> <p>Background</p> <p>We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In thi...

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Detalhes bibliográficos
Main Authors: Waraya Mina, Yamashita Keishi, Katoh Hiroshi, Ooki Akira, Kawamata Hiroshi, Nishimiya Hiroshi, Nakamura Kazunori, Ema Akira, Watanabe Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-09-01
Colecção:BMC Cancer
Assuntos:
HOP homeobox
Pancreatic cancer
Methylation
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/397
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