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Solid-Phase Synthesis of Lysobactin (Katanosin B): Insights into Structure and Function

[Image: see text] The solid phase synthesis of the cyclic depsipeptide antibiotic lysobactin is described. The natural product was synthesized via a linear approach using mostly Fmoc-strategy solid phase peptide synthesis (SPPS) with a single purification. A lysobactin analog has also been synthesiz...

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Autori principali: Hall, Edward A., Kuru, Erkin, VanNieuwenhze, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488444/
https://ncbi.nlm.nih.gov/pubmed/22612400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300926d
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