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Regulated Noise in the Epigenetic Landscape of Development and Disease

In this Perspective, we synthesize past and present observations in the field of epigenetics to propose a model in which the epigenome can modulate cellular plasticity in development and disease by regulating the effects of noise. In this model, the epigenome facilitates phase transitions in develop...

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Bibliografski detalji
Glavni autori: Pujadas, Elisabet, Feinberg, Andrew
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488344/
https://ncbi.nlm.nih.gov/pubmed/22424224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.045
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