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Regulated Noise in the Epigenetic Landscape of Development and Disease
In this Perspective, we synthesize past and present observations in the field of epigenetics to propose a model in which the epigenome can modulate cellular plasticity in development and disease by regulating the effects of noise. In this model, the epigenome facilitates phase transitions in develop...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488344/ https://ncbi.nlm.nih.gov/pubmed/22424224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.045 |
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