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Regulated Noise in the Epigenetic Landscape of Development and Disease

In this Perspective, we synthesize past and present observations in the field of epigenetics to propose a model in which the epigenome can modulate cellular plasticity in development and disease by regulating the effects of noise. In this model, the epigenome facilitates phase transitions in develop...

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Detalles Bibliográficos
Autores principales: Pujadas, Elisabet, Feinberg, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488344/
https://ncbi.nlm.nih.gov/pubmed/22424224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.045
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