Llwytho...

Regulated Noise in the Epigenetic Landscape of Development and Disease

In this Perspective, we synthesize past and present observations in the field of epigenetics to propose a model in which the epigenome can modulate cellular plasticity in development and disease by regulating the effects of noise. In this model, the epigenome facilitates phase transitions in develop...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pujadas, Elisabet, Feinberg, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488344/
https://ncbi.nlm.nih.gov/pubmed/22424224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.045
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