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Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses
In this review, we discuss how working memory prefrontal cortical (PFC) circuits are modulated differently than plastic changes in sensory/motor and subcortical circuits. Working memory arises from recurrent excitation within layer III PFC pyramidal cell NMDA circuits, which are afflicted in aging a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488343/ https://ncbi.nlm.nih.gov/pubmed/23040817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.08.038 |
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