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Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments
Genomic experiments (e.g. differential gene expression, single-nucleotide polymorphism association) typically produce ranked list of genes. We present a simple but powerful approach which uses protein–protein interaction data to detect sub-networks within such ranked lists of genes or proteins. We p...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488210/ https://ncbi.nlm.nih.gov/pubmed/22844098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks699 |
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