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Conjugation of Y. pestis F1-antigen to gold nanoparticles improves immunogenicity
The efficacy of 15 nm gold nanoparticles (AuNP) coated with Yersinia pestis F1-antigen, as an immunogen in mice, has been assessed. The nanoparticles were decorated with F1-antigen using N-hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide coupling chemistry. Mice given AuNP-F1 in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488157/ https://ncbi.nlm.nih.gov/pubmed/23000121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.09.021 |
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