The Obestatin/GPR39 System Is Up-regulated by Muscle Injury and Functions as an Autocrine Regenerative System

The maintenance and repair of skeletal muscle are attributable to an elaborate interaction between extrinsic and intrinsic regulatory signals that regulate the myogenic process. In the present work, we showed that obestatin, a 23-amino acid peptide encoded by the ghrelin gene, and the GPR39 receptor...

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Main Authors: Gurriarán-Rodríguez, Uxía, Santos-Zas, Icía, Al-Massadi, Omar, Mosteiro, Carlos S., Beiroa, Daniel, Nogueiras, Rubén, Crujeiras, Ana B., Seoane, Luisa M., Señarís, José, García-Caballero, Tomás, Gallego, Rosalía, Casanueva, Felipe F., Pazos, Yolanda, Camiña, Jesús P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488106/
https://ncbi.nlm.nih.gov/pubmed/22992743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374926
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