The Obestatin/GPR39 System Is Up-regulated by Muscle Injury and Functions as an Autocrine Regenerative System

The maintenance and repair of skeletal muscle are attributable to an elaborate interaction between extrinsic and intrinsic regulatory signals that regulate the myogenic process. In the present work, we showed that obestatin, a 23-amino acid peptide encoded by the ghrelin gene, and the GPR39 receptor...

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Autores principales: Gurriarán-Rodríguez, Uxía, Santos-Zas, Icía, Al-Massadi, Omar, Mosteiro, Carlos S., Beiroa, Daniel, Nogueiras, Rubén, Crujeiras, Ana B., Seoane, Luisa M., Señarís, José, García-Caballero, Tomás, Gallego, Rosalía, Casanueva, Felipe F., Pazos, Yolanda, Camiña, Jesús P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488106/
https://ncbi.nlm.nih.gov/pubmed/22992743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374926
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