Crystal Structure of the VgrG1 Actin Cross-linking Domain of the Vibrio cholerae Type VI Secretion System

Vibrio cholerae is the cause of the diarrheal disease cholera. V. cholerae produces RtxA, a large toxin of the MARTX family, which is targeted to the host cell cytosol, where its actin cross-linking domain (ACD) cross-links G-actin, leading to F-actin depolymerization, cytoskeleton rearrangements, a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Durand, Eric, Derrez, Estelle, Audoly, Gilles, Spinelli, Silvia, Ortiz-Lombardia, Miguel, Raoult, Didier, Cascales, Eric, Cambillau, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488088/
https://ncbi.nlm.nih.gov/pubmed/22898822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390153
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