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Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike

The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes a tube topped by a spike into target cells. Effectors...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Flaugnatti, Nicolas, Rapisarda, Chiara, Rey, Martial, Beauvois, Solène G, Nguyen, Viet Anh, Canaan, Stéphane, Durand, Eric, Chamot‐Rooke, Julia, Cascales, Eric, Fronzes, Rémi, Journet, Laure
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265238/
https://ncbi.nlm.nih.gov/pubmed/32350888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104129
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