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Negative Regulation of AMP-activated Protein Kinase (AMPK) Activity by Macrophage Migration Inhibitory Factor (MIF) Family Members in Non-small Cell Lung Carcinomas

AMP-activated protein kinase (AMPK) is a nutrient- and metabolic stress-sensing enzyme activated by the tumor suppressor kinase, LKB1. Because macrophage migration inhibitory factor (MIF) and its functional homolog, d-dopachrome tautomerase (d-DT), have protumorigenic functions in non-small cell lun...

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Detalhes bibliográficos
Main Authors: Brock, Stephanie E., Rendon, Beatriz E., Yaddanapudi, Kavitha, Mitchell, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488063/
https://ncbi.nlm.nih.gov/pubmed/22988252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378299
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