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Gene Duplication and the Evolution of Hemoglobin Isoform Differentiation in Birds

The majority of bird species co-express two functionally distinct hemoglobin (Hb) isoforms in definitive erythrocytes as follows: HbA (the major adult Hb isoform, with α-chain subunits encoded by the α(A)-globin gene) and HbD (the minor adult Hb isoform, with α-chain subunits encoded by the α(D)-glo...

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Autori principali: Grispo, Michael T., Natarajan, Chandrasekhar, Projecto-Garcia, Joana, Moriyama, Hideaki, Weber, Roy E., Storz, Jay F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488042/
https://ncbi.nlm.nih.gov/pubmed/22962007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375600
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