L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia

BACKGROUND: Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling. The role of L-citrulline supplementation was investigated in th...

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Hauptverfasser: Sopi, Ramadan B, Zaidi, Syed IA, Mladenov, Mitko, Sahiti, Hazbije, Istrefi, Zahide, Gjorgoski, Icko, Lajçi, Azem, Jakupaj, Muharrem
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487946/
https://ncbi.nlm.nih.gov/pubmed/22870905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-68
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