Role of Arginase in Impairing Relaxation of Lung Parenchyma of Hyperoxia-Exposed Neonatal Rats

BACKGROUND: Prolonged exposure of immature lungs to hyperoxia contributes to neonatal lung injury and airway hyperreactivity. We have previously demonstrated that neonatal exposure of rat pups to ≥95% O(2) impairs airway relaxation due to disruption of nitric oxide (NO)-cyclic guanosine monophosphat...

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Hlavní autoři: Ali, Nuzhat K.M., Jafri, Anjum, Sopi, Ramadan B., Prakash, Y.S., Martin, Richard J., Zaidi, Syed I.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2012
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223066/
https://ncbi.nlm.nih.gov/pubmed/21952491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329540
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