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Effect of nonspecific forces and finite receptor number on rate constants of ligand--cell bound-receptor interactions.

We develop a theory of ligand diffusion in the presence of a central potential toward or away from receptor patches that are uniformly distributed over a spherical cell. The current onto the receptors is reduced to less than that onto the sphere by a factor that is a nonlinear function of the number...

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Detalhes bibliográficos
Main Authors: DeLisi, C, Wiegel, F W
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348789/
https://ncbi.nlm.nih.gov/pubmed/6946494
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