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Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

BACKGROUND: Cellular senescence is a stress response of mammalian cells leading to a durable arrest of cell proliferation that has been implicated in tumor suppression, wound healing, and aging. The proliferative arrest is mediated by transcriptional repression of genes essential for cell division b...

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Autors principals: Contrepois, Kévin, Thuret, Jean-Yves, Courbeyrette, Régis, Fenaille, François, Mann, Carl
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487866/
https://ncbi.nlm.nih.gov/pubmed/22932127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-15
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