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Asymmetric Divergence in Structure and Function of HCN Channel Duplicates in Ciona intestinalis

Hyperpolarization-activated Cyclic Nucleotide (HCN) channels are voltage-gated cation channels and are critical for regulation of membrane potential in electrically active cells. To understand the evolution of these channels at the molecular level, we cloned and examined two of three HCN homologs of...

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Détails bibliographiques
Auteurs principaux: Jackson, Heather A., Hegle, Andrew, Nazzari, Hamed, Jegla, Timothy, Accili, Eric A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487815/
https://ncbi.nlm.nih.gov/pubmed/23133599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047590
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