Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule Biosynthesis

Group A streptococcus (GAS) causes human pharyngitis and invasive infections and frequently colonizes individuals asymptomatically. Many lines of evidence generated over decades have shown that the hyaluronic acid capsule is a major virulence factor contributing to these infections. While conducting...

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Main Authors: Flores, Anthony R., Jewell, Brittany E., Fittipaldi, Nahuel, Beres, Stephen B., Musser, James M.
格式: Artigo
語言:Inglês
出版: American Society of Microbiology 2012
主題:
Observation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487777/
https://ncbi.nlm.nih.gov/pubmed/23131832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00413-12
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