Transcription of the Streptococcus pyogenes Hyaluronic Acid Capsule Biosynthesis Operon Is Regulated by Previously Unknown Upstream Elements

The important human pathogen Streptococcus pyogenes (group A Streptococcus [GAS]) produces a hyaluronic acid (HA) capsule that plays critical roles in immune evasion. Previous studies showed that the hasABC operon encoding the capsule biosynthesis enzymes is under the control of a single promoter, P...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Falaleeva, Marina, Zurek, Oliwia W., Watkins, Robert L., Reed, Robert W., Ali, Hadeel, Sumby, Paul, Voyich, Jovanka M., Korotkova, Natalia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249290/
https://ncbi.nlm.nih.gov/pubmed/25287924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02035-14
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