Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid.

The leucine analog beta-2-aminobicyclo[2.2.1]heptane-2-carboxylic acid (BCH) activates glutamate dehydrogenase [L-glutamate:NAD+ oxidoreductase (deaminating), EC 1.4.1.2] in pancreatic islet homogenates. In intact islets, BCH increased the islet content or output of NH4+, 2-ketoglutarate, malate, py...

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Main Authors: Sener, A, Malaisse-Lagae, F, Malaisse, W J
Format: Artigo
Jezik:Inglês
Izdano: 1981
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC348765/
https://ncbi.nlm.nih.gov/pubmed/6117857
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