Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol

Heme-oxygenase 1 is an endoplasmic reticulum-anchored enzyme that breaks down heme into iron, carbon monoxide and biliverdin. Heme is a hydrophobic co-factor in many proteins, including hemoglobin. Free heme is highly cytotoxic and, therefore, both heme synthesis and breakdown are tightly regulated....

Full description

Saved in:
Bibliographic Details
Main Authors: Gottlieb, Yehonatan, Truman, Marianna, Cohen, Lyora A., Leichtmann-Bardoogo, Yael, Meyron-Holtz, Esther G.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2012
Subjects:
Original Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487549/
https://ncbi.nlm.nih.gov/pubmed/22419571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.063651
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items