Genetic and Epigenetic Variations in Inducible Nitric Oxide Synthase Promoter, Particulate Pollution and Exhaled Nitric Oxide in Children

BACKGROUND: Inducible nitric oxide synthase (iNOS, encoded by NOS2) is the major enzyme for nitric oxide synthesis in airways. As such, measurement of exhaled nitric oxide (FeNO) provides an in vivo assessment of iNOS activity. Short-term exposure to air pollution, haplotypes and DNA methylation in...

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Main Authors: Salam, Muhammad T., Byun, Hyang-Min, Lurmann, Fred, Breton, Carrie V., Wang, Xinhui, Eckel, Sandrah P., Gilliland, Frank D.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487398/
https://ncbi.nlm.nih.gov/pubmed/22055874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.09.037
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