Microparticles Induce Cell Cycle Arrest Through Redox-Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

BACKGROUND: Chronic disease accelerates endothelial dysfunction in aging, a process associated with cell senescence. However, the mechanisms underlying this process are unclear. We examined whether endothelial cell (EC)-derived microparticles (MPs) facilitate EC senescence and questioned the role of...

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Bibliographic Details
Main Authors: Burger, Dylan, Kwart, Dylan G., Montezano, Augusto C., Read, Naomi C., Kennedy, Christopher R.J., Thompson, Charlie S., Touyz, Rhian M.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487329/
https://ncbi.nlm.nih.gov/pubmed/23130145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.001842
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