Functional Characterization of an scFv-Fc Antibody that Immunotherapeutically Targets the Common Cancer Cell Surface Proteoglycan CSPG4

Cell surface chondroitin sulfate proteoglycan 4 (CSPG4) is an attractive target for antibody-based cancer immunotherapy because of its role in tumor cell biology, its high expression on malignant cells including cancer-initiating cells, and its restricted distribution in normal tissues. The clinical...

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Huvudupphovsmän: Wang, Xinhui, Katayama, Akihiro, Wang, Yangyang, Yu, Ling, Favoino, Elvira, Sakakura, Koichi, Favole, Alessandra, Tsuchikawa, Takahiro, Silver, Susan, Watkins, Simon C., Kageshita, Toshiro, Ferrone, Soldano
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487169/
https://ncbi.nlm.nih.gov/pubmed/22021902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1134
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