Tumorigenic transformation induced by a specific fragment of DNA from herpes simplex virus type 2.

Transfection of Syrian hamster embryo cells with limit digests of Bgl II-, Hpa I-, or Bgl II/Hpa I-cleaved DNA from herpes simplex virus type 2 (strain S-1) but not with salmon sperm DNA resulted in the appearance of refractile, morphologically altered cells at a frequency of 10(-5)/0.005 microgram...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jariwalla, R J, Aurelian, L, Ts'o, P O
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348697/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2279
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