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Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.

Two distinct loci that confer resistance to acycloguanosine (acyclo-Guo) in herpes simplex virus types 1 have been identified. The first locus is the gene for the virus-specific thymidine kinase (TK). Mutations that decrease TK activity also render the virus resistant to acyclo-Guo, and the level of...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Coen, D M, Schaffer, P A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1980
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2265
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