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Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.

Two distinct loci that confer resistance to acycloguanosine (acyclo-Guo) in herpes simplex virus types 1 have been identified. The first locus is the gene for the virus-specific thymidine kinase (TK). Mutations that decrease TK activity also render the virus resistant to acyclo-Guo, and the level of...

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Bibliografske podrobnosti
Main Authors: Coen, D M, Schaffer, P A
Format: Artigo
Jezik:Inglês
Izdano: 1980
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC348694/
https://ncbi.nlm.nih.gov/pubmed/6246531
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