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Histone H1 Plays a Role in Heterochromatin Formation and VSG Expression Site Silencing in Trypanosoma brucei

The African sleeping sickness parasite Trypanosoma brucei evades the host immune system through antigenic variation of its variant surface glycoprotein (VSG) coat. Although the T. brucei genome contains ∼1500 VSGs, only one VSG is expressed at a time from one of about 15 subtelomeric VSG expression...

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Bibliografische gegevens
Hoofdauteurs: Povelones, Megan L., Gluenz, Eva, Dembek, Marcin, Gull, Keith, Rudenko, Gloria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486875/
https://ncbi.nlm.nih.gov/pubmed/23133390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003010
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