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In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel located primarily at the apical membranes of epithelial cells, plays a crucial role in transepithelial fluid homeostasis(1-3). CFTR has been implicated in two major diseases: cystic fibrosis (CF)(4) and secretory diarrhea...

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Detalhes bibliográficos
Main Authors: Wu, Yanning, Wang, Shuo, Li, Chunying
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486763/
https://ncbi.nlm.nih.gov/pubmed/22907480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4091
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