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The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells

RhoA protein is involved in the Ca(2+) sensitization of bronchial smooth muscle (BSM) contraction, and an upregulation of RhoA in BSMs has been suggested in allergic bronchial asthma. However, the mechanism of upregulation of RhoA remains poorly understood. In the present study, the transcriptional...

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Bibliografski detalji
Glavni autori: Goto, Kumiko, Chiba, Yoshihiko, Matsusue, Kimihiko, Hattori, Yoshiyuki, Maitani, Yoshie, Sakai, Hiroyasu, Kimura, Shioko, Misawa, Miwa
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486725/
https://ncbi.nlm.nih.gov/pubmed/20006706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2009.12.001
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