The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells

RhoA protein is involved in the Ca(2+) sensitization of bronchial smooth muscle (BSM) contraction, and an upregulation of RhoA in BSMs has been suggested in allergic bronchial asthma. However, the mechanism of upregulation of RhoA remains poorly understood. In the present study, the transcriptional...

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Bibliographische Detailangaben
Hauptverfasser: Goto, Kumiko, Chiba, Yoshihiko, Matsusue, Kimihiko, Hattori, Yoshiyuki, Maitani, Yoshie, Sakai, Hiroyasu, Kimura, Shioko, Misawa, Miwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486725/
https://ncbi.nlm.nih.gov/pubmed/20006706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2009.12.001
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