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Corifungin, a New Drug Lead against Naegleria, Identified from a High-Throughput Screen

Primary amebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living ameba Naegleria fowleri. The drug of choice in treating PAM is the antifungal antibiotic amphotericin B, but its use is associated with severe adverse effects. Moreover, few patients treated with amphoter...

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Bibliografiset tiedot
Päätekijät: Debnath, Anjan, Tunac, Josefino B., Galindo-Gómez, Silvia, Silva-Olivares, Angélica, Shibayama, Mineko, McKerrow, James H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486592/
https://ncbi.nlm.nih.gov/pubmed/22869574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00643-12
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