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Corifungin, a New Drug Lead against Naegleria, Identified from a High-Throughput Screen
Primary amebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living ameba Naegleria fowleri. The drug of choice in treating PAM is the antifungal antibiotic amphotericin B, but its use is associated with severe adverse effects. Moreover, few patients treated with amphoter...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486592/ https://ncbi.nlm.nih.gov/pubmed/22869574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00643-12 |
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